Serwane Group
Welcome to the Serwane Research Group on mechanobiology and neuronal networks
Our team integrates concepts of physics and biology to develop a model system for a retinal neuronal network.
The high accessibility and tunability of our in vitro system will allow us to address fundamental questions at the interface between physics and biology:
- What are the mechanical cues that guide the self-organization of retina tissues?
- How are light-induced neuronal signals processed within these tissues?
- Can we use these systems as powerful in vitro disease models?
To address these questions we join forces with the Soft Condensed Matter Group at the Department of Physics at LMU and the Munich Cluster for Systems Neurology (SyNergy).
To illuminate the role of mechanics, we will use ferrofluid droplets as mechanical actuators, a technique which has been developed by us (Serwane et al., Nature Methods, 2017) and has been used to understand the role of mechanics in 3D developing tissues (Mongera et al., Nature 2018).
Related Links
Publications
Find a list of all publications by the Serwane Group on this page.
Open Positions
If you are interested in joining the lab, please take a look at our open positions.
Theses collection
Physics
- Light-sheet microscopy of 3D activity in neural organoids, 2022
Physics
- Quantification of Glioblastoma Mechanics in Brain Organoids Using Ferrofluid Droplets, 2023
- Statistical Analysis of Network Activity in Mouse Retinal Organoids, 2023
- An Open-top Oblique Light-sheet Microscope for Neural Network Imaging, 2023
- A Scalable Pipeline for Volumetric Calcium Imaging Analysis, 2022
Molecular Biotechnology
- Characterization of Amyloid β plaque formation in vitro, 2022
Physics
- Simulation and Development of a Microfluidic Biochip to Cultivate Organoids, 2022
Medizintechnik
- An incubation chamber for retinal organoid imaging, 2017
Group members
| Name | Position |
|---|---|
| Serwane, Friedhelm | Chair of Experimental Physics - Soft Condensed Matter |
| Volkov, Georgii | Master Student |
| Brinkop, Achim | PhD Student |
| Frischmann, Michael | PhD Student |
| Hadalin, Vlasta | PhD Student |
| Rogler, Teresa | PhD Student |
| Shelton, Elijah | Postdoc |
| Lackmann, Marie | Technical Assistant |
Alumni
| Name | Position |
|---|---|
| James, Rebecca | Technical Assistant |
| Rose, Roland | Technical Assistant |
| Schorre, Florian | Technical Assistant |
| Sonntag, Selina | Technical Assistant |
| Glanz, Lena | Graduate Assistant |
| Göcergi, Ziya | Bachelor Student |
| Kiessler, Filippo | Master Student |
| Thielen, Alina | Master Student |
| Willenberg, Sebastian | Master Student |
| Salbaum, Katja | PhD Student |
| Wysmołek, Paulina | PhD Student |
| Gallali, Mariam | Intern |