Rädler Group: new review on cell migration
22 Apr 2024
'Mesenchymal cell migration on one-dimensional micropatterns'
22 Apr 2024
'Mesenchymal cell migration on one-dimensional micropatterns'
We are excited to see our review article on 1D cell migration published in Frontiers in Cell and Developmental Biology. Our understanding of cell migration has immensely profited from studying cells move in one-dimensional confinements, such as on microfabricated lanes. In our article we review 1D migration assays, reflect on the advantages of such platforms and discuss popular biophysical models of cell migration. We highlight the unique opportunity of reproducible and standardised 1D assays to validate theory based on statistical measures from large data of trajectories and discuss the potential of experimental settings embedding controlled perturbations to probe response in migratory behaviour.
Johannes C. J. Heyn, Joachim O. Rädler, Martin Falcke
Mesenchymal cell migration on one-dimensional micropatterns
Front. Cell Dev. Biol., Sec. Cell Adhesion and Migration, Volume 12, 2024